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Vc-MMAD

Vc-MMAD consists the ADCs linker (Val-Cit) and potent tubulin inhibitor (MMAD) . Vc-MMAD is a agent-linker conjugate for ADC.

Product Specifications

CAS Number

1401963-17-4

UNSPSC

12352203

Hazard Statement

H302, H315, H319

Target

Drug-Linker Conjugates for ADC; Microtubule/Tubulin

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Vc-MMAD.html

Purity

99.96

Solubility

DMSO : ≥ 160 mg/mL

Smiles

O=C1N(CCCCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(COC(N([C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@H]([C@@H](CC(N3[C@@H](CCC3)[C@H](OC)[C@H](C(N[C@H](C4=NC=CS4)CC5=CC=CC=C5)=O)C)=O)OC)[C@@H](C)CC)C)=O)=O)C)=O)C=C2)=O)=O)=O)C(C=C1)=O

Molecular Formula

C70H104N12O14S

Molecular Weight

1369.71

Precautions

H302, H315, H319

References & Citations

[1]Antibody-drug conjugates Patent: WO 2013068874 A1

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Auristatin

Available Sizes

Frequently Asked Questions

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