Vc-MMAD
Vc-MMAD consists the ADCs linker (Val-Cit) and potent tubulin inhibitor (MMAD) . Vc-MMAD is a agent-linker conjugate for ADC.
Product Specifications
CAS Number
[1401963-17-4]
UNSPSC
12352203
Hazard Statement
H302, H315, H319
Target
Drug-Linker Conjugates for ADC; Microtubule/Tubulin
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Vc-MMAD.html
Purity
99.96
Solubility
DMSO : ≥ 160 mg/mL
Smiles
O=C1N(CCCCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(COC(N([C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@H]([C@@H](CC(N3[C@@H](CCC3)[C@H](OC)[C@H](C(N[C@H](C4=NC=CS4)CC5=CC=CC=C5)=O)C)=O)OC)[C@@H](C)CC)C)=O)=O)C)=O)C=C2)=O)=O)=O)C(C=C1)=O
Molecular Formula
C70H104N12O14S
Molecular Weight
1369.71
Precautions
H302, H315, H319
References & Citations
[1]Antibody-drug conjugates Patent: WO 2013068874 A1
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Auristatin
Available Sizes
Curated Selection
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