H-Arg-OtBu (dihydrochloride)

H-Arg-OtBu (dihydrochloride) is a membrane-targeting antimicrobial. H-Arg-OtBu (dihydrochloride) targets the negatively charged bacterial membrane via a combination of electrostatic and hydrophobic interactions. H-Arg-OtBu (dihydrochloride) can be used for bacterial infections diseases research[1].

Product Specifications

CAS Number

[87459-72-1]

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

Antibiotic

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/h-arg-otbu-dihydrochloride.html

Solubility

10 mM in DMSO

Smiles

CC(C)(OC([C@@H](N)CCCNC(N)=N)=O)C.Cl.Cl

Molecular Formula

C10H24Cl2N4O2

Molecular Weight

303.23

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Koh JJ, et al, Beuerman RW. Amino acid modified xanthone derivatives: novel, highly promising membrane-active antimicrobials for multidrug-resistant Gram-positive bacterial infections. J Med Chem. 2015 Jan 22;58 (2) :739-52.