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CD86 Antibody

Mouse monoclonal antibody to CD86

Product Specifications

Product Name Alternative

Activation B7-2 antigen; B lymphocyte activation antigen B72; CD28 antigen ligand 2; CD28LG2; CLS1; CTLA-4 counter-receptor B7.2; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly-58; MB7-2; TS/A-2

UniProt

P42081

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant human full-length CD86 protein

Target

CD86

Clonality

Monoclonal

Clone

C86/1146

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Purification

Protein G

Dilution

FACS: 0.5-1 μg/million cells, IF/ICC: 0.5-1 μg/ml, WB: 0.5-1 μg/ml, IHC-P: 2-4 μg/ml

Form

200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.

Molecular Weight

70kDa

References & Citations

Bing Lu et al. Targeting the tumor microenvironment: reprogramming macrophages as a novel therapeutic strategy in FUOM-deficient glioblastoma Cell Death Dis ., (2026), Qiming Gu1 Jiali Shan1 Yan Li2 Zhengyi Lian1 Tang Liu1 Lei Yang2 Bingyi Liu1 Kefan Wu1 Xuan Li1 Qichao Ni1 Jun Fang1 DAPP1 Elevated Expression Influences Macrophages and Predicts Poor Prognosis in Breast Cancer researchsquare.com, (2025), Yu X., Xu L., Zhou Y., Zhou X, Yang L., Zhou Y. NUP62CL as an Immunological and Prognostic Biomarker of Oral Squamous Cell Carcinoma Dove Medical Press, 16, 3799-3809 (2023), Saba Ahangaran, Arash Pourgholaminejad, Rahim Nosrati, Parvin Babaei TLR4 inhibition attenuates facilitatory effects of JQ1 on learning & memory via polarization of microglia, and BDNF expression in Alzheimer's disease model Behav Brain Res, 499, 115919 (2026), Guying He et al. Vesicle trafficking 1 in breast cancer tissue and serum orchestrates metastatic progression and an immunosuppressive microenvironment Int Immunopharmacol, (2026)

Pubmed id

41957358, 41218737, 41915991

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

CD86 (Dendritic Cells Maturation Marker)

Tested Applications

IF, IHC, WB

Host or Source

Mouse

Isotype

IgG1

Available Sizes

Frequently Asked Questions

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