CD86 Antibody
Mouse monoclonal antibody to CD86
Product Specifications
Product Name Alternative
Activation B7-2 antigen; B lymphocyte activation antigen B72; CD28 antigen ligand 2; CD28LG2; CLS1; CTLA-4 counter-receptor B7.2; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly-58; MB7-2; TS/A-2
UniProt
P42081
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human full-length CD86 protein
Target
CD86
Clonality
Monoclonal
Clone
C86/1146
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Protein G
Dilution
FACS: 0.5-1 μg/million cells, IF/ICC: 0.5-1 μg/ml, WB: 0.5-1 μg/ml, IHC-P: 2-4 μg/ml
Form
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
Molecular Weight
70kDa
References & Citations
Bing Lu et al. Targeting the tumor microenvironment: reprogramming macrophages as a novel therapeutic strategy in FUOM-deficient glioblastoma Cell Death Dis ., (2026), Qiming Gu1 Jiali Shan1 Yan Li2 Zhengyi Lian1 Tang Liu1 Lei Yang2 Bingyi Liu1 Kefan Wu1 Xuan Li1 Qichao Ni1 Jun Fang1 DAPP1 Elevated Expression Influences Macrophages and Predicts Poor Prognosis in Breast Cancer researchsquare.com, (2025), Yu X., Xu L., Zhou Y., Zhou X, Yang L., Zhou Y. NUP62CL as an Immunological and Prognostic Biomarker of Oral Squamous Cell Carcinoma Dove Medical Press, 16, 3799-3809 (2023), Saba Ahangaran, Arash Pourgholaminejad, Rahim Nosrati, Parvin Babaei TLR4 inhibition attenuates facilitatory effects of JQ1 on learning & memory via polarization of microglia, and BDNF expression in Alzheimer's disease model Behav Brain Res, 499, 115919 (2026), Guying He et al. Vesicle trafficking 1 in breast cancer tissue and serum orchestrates metastatic progression and an immunosuppressive microenvironment Int Immunopharmacol, (2026)
Pubmed id
41957358, 41218737, 41915991
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
CD86 (Dendritic Cells Maturation Marker)
Tested Applications
IF, IHC, WB
Host or Source
Mouse
Isotype
IgG1
Available Sizes
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