Ribociclib acetate
Ribociclib acetate is a degradation product of Ribociclib under acid-base hydrolysis conditions. Ribociclib acetate has been predicted to be carcinogenic[1].
Product Specifications
CAS Number
2762182-61-4
UNSPSC
12352005
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ribociclib-acetate.html
Solubility
DMSO : 4 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC2=C(N1C3CCCC3)N=C(NC4=NC=C(N5CCNCC5)C=C4)N=C2)O
Molecular Formula
C21H25N7O2
Molecular Weight
407.47
References & Citations
[1]Sahu AK, et al. Identification and structural characterization of potential degraded impurities of ribociclib by time of flight -tandem mass spectrometry, and their toxicity prediction. J Pharm Biomed Anal. 2021 Apr 15;197:113933.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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