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Ribociclib acetate

Ribociclib acetate is a degradation product of Ribociclib under acid-base hydrolysis conditions. Ribociclib acetate has been predicted to be carcinogenic[1].

Product Specifications

CAS Number

2762182-61-4

UNSPSC

12352005

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ribociclib-acetate.html

Solubility

DMSO : 4 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=CC2=C(N1C3CCCC3)N=C(NC4=NC=C(N5CCNCC5)C=C4)N=C2)O

Molecular Formula

C21H25N7O2

Molecular Weight

407.47

References & Citations

[1]Sahu AK, et al. Identification and structural characterization of potential degraded impurities of ribociclib by time of flight -tandem mass spectrometry, and their toxicity prediction. J Pharm Biomed Anal. 2021 Apr 15;197:113933.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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