Smurf1 modulator-1
Smurf1 modulator-1 (Compound 20) is a selective inhibitor for Smad ubiquitination regulatory factor 1 (Smurf1), with IC50 of 180 nM[1].
Product Specifications
CAS Number
[1825371-51-4]
UNSPSC
12352005
Target
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/smurf1-modulator-1.html
Purity
99.76
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C1N(C2CCCCC2)N(C(C)=C1NC(C3=NOC([C@H]4[C@@H](OC(C)(CO4)C)C)=C3C)=O)C
Molecular Formula
C23H34N4O5
Molecular Weight
446.54
References & Citations
[1]A D'souza, et al., Carboxamide derivatives. WO2015175796.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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