(5-Cl) -Exatecan
(5-Cl) -Exatecan (compound 1-5) is a potent DNA topoisomerase inhibitor used in cancer research. (5-Cl) -Exatecan is an ADC Cytotoxin[1].
Product Specifications
CAS Number
[2813268-66-3]
UNSPSC
12352005
Target
ADC Payload; Topoisomerase
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-cl-exatecan.html
Smiles
N[C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(Cl)=C(C)C(CC1)=C62
Molecular Formula
C24H22ClN3O4
Molecular Weight
451.90
References & Citations
[1]Haijun Tian, et al. Antibody drug conjugate, and preparation method therefor and use thereof. WO2022253035A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Camptothecins
Curated Selection
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