(5-Cl) -Exatecan
(5-Cl) -Exatecan (compound 1-5) is a potent DNA topoisomerase inhibitor used in cancer research. (5-Cl) -Exatecan is an ADC Cytotoxin[1].
Product Specifications
CAS Number
[2813268-66-3]
UNSPSC
12352005
Target
ADC Payload; Topoisomerase
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-cl-exatecan.html
Smiles
N[C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(Cl)=C(C)C(CC1)=C62
Molecular Formula
C24H22ClN3O4
Molecular Weight
451.90
References & Citations
[1]Haijun Tian, et al. Antibody drug conjugate, and preparation method therefor and use thereof. WO2022253035A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Camptothecins
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