EBET-590
EBET-590 is a BET inhibitor, and can be used for cancer research[1]
Product Specifications
CAS Number
[3031540-40-3]
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ebet-590.html
Solubility
10 mM in DMSO
Smiles
OC[C@](OC1CC1)(C2=CC=CC=C2)C3=NC(N)=NC4=CC=C(C(C=C5C)=CN(C)C5=O)C=C43
Molecular Formula
C26H26N4O3
Molecular Weight
442.51
References & Citations
[1]Nakazawa Y, et al. Delivery of a BET protein degrader via a CEACAM6-targeted antibody-drug conjugate inhibits tumour growth in pancreatic cancer models. Nat Commun. 2024 Mar 11;15 (1) :2192.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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