K-TMZ

K-TMZ is a derivative of methyl ketone, which exhibits antitumor efficacy against O6 -methylguanine DNA methyltransferase (MGMT) deficient cell. K-TMZ can be used for research of glioblastoma[1].

Product Specifications

CAS Number

[2269482-26-8]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/k-tmz.html

Smiles

O=C(N(C)N=N1)N2C1=C(C(C)=O)N=C2

Molecular Formula

C7H7N5O2

Molecular Weight

193.16

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Svec RL, et al., Tunable Stability of Imidazotetrazines Leads to a Potent Compound for Glioblastoma. ACS Chem Biol. 2018 Nov 16;13 (11) :3206-3216.