K-TMZ
K-TMZ is a derivative of methyl ketone, which exhibits antitumor efficacy against O6 -methylguanine DNA methyltransferase (MGMT) deficient cell. K-TMZ can be used for research of glioblastoma[1].
Product Specifications
CAS Number
[2269482-26-8]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/k-tmz.html
Smiles
O=C(N(C)N=N1)N2C1=C(C(C)=O)N=C2
Molecular Formula
C7H7N5O2
Molecular Weight
193.16
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Svec RL, et al., Tunable Stability of Imidazotetrazines Leads to a Potent Compound for Glioblastoma. ACS Chem Biol. 2018 Nov 16;13 (11) :3206-3216.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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