Trh-gly

Trh-gly (TRH-glycine) is a precursor of thyrotropin (TSH) -releasing hormone (TRH) that can release thyrotropin and prolactin[1].

Product Specifications

CAS Number

[85344-77-0]

Product Name Alternative

TRH-glycine

UNSPSC

12352209

Hazard Statement

H302-H315-H319-H335

Target

Thyroid Hormone Receptor

Type

Peptides

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/trh-gly.html

Solubility

10 mM in DMSO

Smiles

O=C([C@@H]1CCC(N1)=O)N[C@@H](CC2=CN=CN2)C(N3[C@@H](CCC3)C(NCC(O)=O)=O)=O

Molecular Formula

C18H24N6O6

Molecular Weight

420.42

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]A E Pekary, et al. Release of thyrotropin and prolactin by a thyrotropin-releasing hormone (TRH) precursor, TRH-Gly: conversion to TRH is sufficient for in vivo effects. Neuroendocrinology. 1990 Dec;52 (6) :618-25. |[2]M Yamada, et al. Activation of the thyrotropin-releasing hormone (TRH) receptor by a direct precursor of TRH, TRH-Gly. Neurosci Lett. 1995 Aug 18;196 (1-2) :109-12.