Cbl-b-IN-19
Cbl-b-IN-19 (Compound 49) is an inhibitor for casitas B-lineage lymphoma b (Cbl-b), that inhibits Cbl-b phosphorylation with an IC50 [1].
Product Specifications
UNSPSC
12352005
Target
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cbl-b-in-19.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC=C(C2=CC(C3CC3)=NC(N4C=NC5=C(C=C(CN6C[C@@H](C)CCC6)C=C5C(F)(F)F)C4=O)=C2)C(C7=NN=CN7C)=C1
Molecular Formula
C34H31F3N8O
Molecular Weight
624.66
References & Citations
[1]Murugan C, et al., Bicyclic heterocyclic compounds as cbl-b inhibitors. WO2024062363A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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