Indobufen (sodium)

Indobufen sodium is a platelet aggregation inhibitor. Indobufen sodium is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen sodium suppresses thromboxane A2 (TxA2) synthesis. Indobufen sodium down-regulates tissue factor (TF) in monocytes[1].

Product Specifications

CAS Number

[94135-04-3]

Product Name Alternative

Ibustrin (sodium)

UNSPSC

12352005

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/indobufen-sodium.html

Smiles

O=C(C(CC)C1=CC=C(N2C(C3=C(C2)C=CC=C3)=O)C=C1)O[Na]

Molecular Formula

C18H16NNaO3

Molecular Weight

317.31

References & Citations

[1]Eligini S, et al. Indobufen inhibits tissue factor in human monocytes through a thromboxane-mediated mechanism. Cardiovasc Res. 2006 Jan;69 (1) :218-26.