TLR3, Mouse (705a.a, HEK293, His)

TLR3 protein is an important component of innate and adaptive immunity and can recognize pathogen-associated molecular patterns and activate NF-κ-B, IRF3 and cytokine secretion. Ligand binding induces TLR3 dimerization, and efficient signal transduction requires clustering of signaling units along the ligand. TLR3 Protein, Mouse (705a.a, HEK293, His) is the recombinant mouse-derived TLR3 protein, expressed by HEK293 , with C-His labeled tag.