1,2-Didecanoyl-sn-glycero-3-phosphoethanolamine
1,2-Didecanoyl-sn-glycero-3-phosphoethanolamine, a phospholipid, showes very promising P-gp inhibitory results at a concentration of 0.3 mM.
Product Specifications
CAS Number
[253685-27-7]
Product Name Alternative
10:0 PE
UNSPSC
12352200
Hazard Statement
H302-H315-H319-H335
Target
Liposome
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/1-2-didecanoyl-sn-glycero-3-phosphoethanolamine.html
Smiles
CCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCCN)OC(=O)CCCCCCCCC
Molecular Formula
C25H50NO8P
Molecular Weight
523.64
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Simon S, Schubert R. Inhibitory effect of phospholipids on P-glycoprotein: cellular studies in Caco-2, MDCKII mdr1 and MDCKII wildtype cells and P-gp ATPase activity measurements. Biochim Biophys Acta. 2012;1821 (9) :1211-1223.
Shipping Conditions
Room temperature
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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