(R) -Oxybutynin (hydrochloride)

(R) -Oxybutynin hydrochloride, a (R) -isomer of Oxybutynin hydrochloride, is an orally active muscarinic receptor antagonist. (R) -Oxybutynin hydrochloride has antimuscarinic, antispasmodic and anticholinergic activity, competitively antagonizes Carbachol-induced contractions. (R) -Oxybutynin hydrochloride can be used for researching incontinence due to neurogenic bladder dysfunction[1][2][3]. (R) -Oxybutynin (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[1207344-05-5]

Product Name Alternative

Aroxybutynin (hydrochloride)

UNSPSC

12352005

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/r-oxybutynin-hydrochloride.html

Purity

98.19

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C([C@](C1=CC=CC=C1)(C2CCCCC2)O)OCC#CCN(CC)CC.[H]Cl

Molecular Formula

C22H32ClNO3

Molecular Weight

393.95

References & Citations

[1]Smith ER, et al. Comparison of the antimuscarinic and antispasmodic actions of racemic oxybutynin and desethyloxybutynin and their enantiomers with those of racemic terodiline. Arzneimittelforschung. 1998 Oct;48 (10) :1012-8. |[2]Siddiqui MA, et al. Oxybutynin extended-release: a review of its use in the management of overactive bladder. Drugs. 2004;64 (8) :885-912. |[3]Zobrist RH, et al. Pharmacokinetics of the R- and S-enantiomers of oxybutynin and N-desethyloxybutynin following oral and transdermal administration of the racemate in healthy volunteers. Pharm Res. 2001 Jul;18 (7) :1029-34.