Zaragozic acid D
Product Specifications
UNSPSC Description
Zaragozic acid D is a squalene synthase inhibitor. Zaragozic acid D also is a farnesyl-protein transferase (FPTase) inhibitor with an IC50 value of 100 nM for bovine FPTase[1][2].
Target Antigen
Farnesyl Transferase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zaragozic-acid-d.html
Smiles
OC([C@]12[C@@H]([C@H]([C@](O1)(O[C@@H]([C@@]2(O)C(O)=O)C(O)=O)CCCC(OC(C)=O)C(C)C/C=C/C3=CC=CC=C3)O)OC(CCCCCCC)=O)=O
Molecular Weight
678.72
References & Citations
[1]Leeyuan Huang, et al. New fungal metabolites as potential antihypercholesterolemics and anticancer agents. Canadian Journal of Botany, 1995, 73(S1): 898-906.|[2]Dufresne C, et al. Zaragozic acids D and D2: potent inhibitors of squalene synthase and of Ras farnesyl-protein transferase. J Nat Prod. 1993 Nov;56(11):1923-9.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-125311/Zaragozic-acid-D-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-125311/
Clinical Information
No Development Reported
CAS Number
155179-14-9
Curated Selection
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