Zaragozic acid D
Zaragozic acid D is a squalene synthase inhibitor. Zaragozic acid D also is a farnesyl-protein transferase (FPTase) inhibitor with an IC50 value of 100 nM for bovine FPTase[1][2].
Product Specifications
CAS Number
155179-14-9
UNSPSC
12352005
Target
Farnesyl Transferase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zaragozic-acid-d.html
Smiles
OC([C@]12[C@@H]([C@H]([C@](O1)(O[C@@H]([C@@]2(O)C(O)=O)C(O)=O)CCCC(OC(C)=O)C(C)C/C=C/C3=CC=CC=C3)O)OC(CCCCCCC)=O)=O
Molecular Formula
C34H46O14
Molecular Weight
678.72
References & Citations
[1]Leeyuan Huang, et al. New fungal metabolites as potential antihypercholesterolemics and anticancer agents. Canadian Journal of Botany, 1995, 73 (S1) : 898-906.|[2]Dufresne C, et al. Zaragozic acids D and D2: potent inhibitors of squalene synthase and of Ras farnesyl-protein transferase. J Nat Prod. 1993 Nov;56 (11) :1923-9.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040029-500 1x 500 µL
Fibronectin (TV-1), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400391-500 1x 500 µL
CD81 / TAPA-1 (1.3.3.22), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC882217-100 1x 100 µL
CD56 / NCAM1 / NKH1 (Neuronal Cell Marker) (NCAM1/2217R), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC741648-100 1x 100 µL
TIMP1 (Marker of Lymph Node Metastasis) (2A5), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 