N6- (4-Methoxybenzyl) adenosine-d3
N6- (4-Methoxybenzyl) adenosine-d3 is deuterium labeled N6- (4-Methoxybenzyl) adenosine. N6- (4-Methoxybenzyl) adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine , Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[2].
Product Specifications
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog
Type
Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Cancer
Smiles
O[C@@H]1[C@@H](CO)O[C@@H](N2C=NC3=C(NCC4=CC=C(OC([2H])([2H])[2H])C=C4)N=CN=C23)[C@@H]1O
Molecular Formula
C18H18D3N5O5
Molecular Weight
390.41
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.|[3]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26 (6) :1490-1500.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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