C[Arg-Arg-Arg-Arg-Dip-Dip-Dip]
C[Arg-Arg-Arg-Arg-Dip-Dip-Dip] (Compound 8C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 12.5 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively[1].
Product Specifications
CAS Number
2619853-87-9
UNSPSC
12352209
Target
Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/c-arg-arg-arg-arg-dip-dip-dip.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@H](C(N[C@@H](C(N[C@@H](C1=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)C(C2=CC=CC=C2)C3=CC=CC=C3)[C@@H](NC([C@@H](NC([C@H](NC([C@H](N1)CCCNC(N)=N)=O)CCCNC(N)=N)=O)C(C4=CC=CC=C4)C5=CC=CC=C5)=O)C(C6=CC=CC=C6)C7=CC=CC=C7
Molecular Formula
C69H87N19O7
Molecular Weight
1294.55
References & Citations
[1]Sandeep Lohan, et al. Small Amphiphilic Peptides: Activity Against a Broad Range of Drug-Resistant Bacteria and Structural Insight into Membranolytic Properties. J Med Chem. 2022 Jan 13;65 (1) :665-687.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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