GW2580-d6
GW2580-d6 is the deuterium labeled GW2580. GW2580 is an orally bioavailable and selective inhibitor of c-Fms kinase which completely inhibits human cFMS kinase in vitro at 0.06 μM. GW2580 acts as a competitive inhibitor of ATP binding to the cFMS kinase and inhibits colony-stimulating-factor-1 signaling[1].
Product Specifications
CAS Number
[2733770-48-2]
UNSPSC
12352005
Target
C-Fms; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others; Protein Tyrosine Kinase/RTK
Field of Research
Inflammation/Immunology; Cancer
Purity
98.36
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
NC1=NC(N)=C(CC2=CC(OC([2H])([2H])[2H])=C(OCC3=CC=C(OC([2H])([2H])[2H])C=C3)C=C2)C=N1
Molecular Formula
C20H16D6N4O3
Molecular Weight
372.45
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
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