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Nav1.7 blocker 1

Nav1.7 blocker 1 (example 41) is a Na+ channel (Nav) blocker with an IC50 value of 0.037 μM. Nav1.7 blocker 1 can be used for the study of pain, including neuropathic pain, postoperative pain, inflammatory pain, and so on[1].

Product Specifications

CAS Number

1426336-36-8

UNSPSC

12352005

Target

Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nav1-7-blocker-1.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=NC(C2=CC=C(OC3=CC=C(C=C3)F)C=C2)=NC(N4CCOCC4CO)=C1)N

Molecular Formula

C22H21FN4O4

Molecular Weight

424.42

References & Citations

[1]Chiyou Ni, et al. Pyrimidines as sodium channel blockers. WIPO. Patent. WO2013030665. 2013-03-07

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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