Rtt109 inhibitor 1
Selected Variant
HY-125969-01
Size: 1 mg
Rtt109 inhibitor 1 (Compound 1) is an inhibitor for histone acetyltransferase Rtt109 through a tight binding, uncompetitive system. Rtt109 inhibitor 1 exhibits antifungal activity through acetylation at H3K56 site[1].
Product Specifications
CAS Number
852935-07-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Fungal; Histone Acetyltransferase
Type
Reference compound
Related Pathways
Anti-infection; Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/rtt109-inhibitor-1.html
Solubility
10 mM in DMSO
Smiles
O=C(N(CC1=C(F)C=CC=C1Cl)C)CN(C(NC2(C3=CC=CC=C3)CCC)=O)C2=O
Molecular Formula
C22H23ClFN3O3
Molecular Weight
431.89
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Lopes da Rosa J, et al., A small molecule inhibitor of fungal histone acetyltransferase Rtt109. Bioorg Med Chem Lett. 2013 May 15;23 (10) :2853-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Price
Frequently Asked Questions
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