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Tussilagone

Tussilagone, a major active component in Tussilago farfara, has anti-inflammatory effect. Tussilagone ameliorates inflammatory responses in dextran sulphate sodium-induced murine colitis. Tussilagone inhibits the inflammatory response and improves survival in cecal ligation and puncture (CLP) -induced septic mice[1][2].

Product Specifications

CAS Number

[104012-37-5]

UNSPSC

12352211

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tussilagone.html

Concentration

10mM

Purity

99.52

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

CC/C(C)=C/C(O[C@H]1C([C@]2([H])CC([C@H]([C@H](OC(C)=O)C)[C@@]2([H])[C@H](C(C)C)C1)=O)=C)=O

Molecular Formula

C23H34O5

Molecular Weight

390.51

References & Citations

[1]Cheon HJ, et al. Tussilagone, a major active component in Tussilago farfara, ameliorates inflammatory responses in dextran sulphate sodium-induced murine colitis. Chem Biol Interact. 2018 Oct 1;294:74-80.|[2]Kim YK, et al. Tussilagone Inhibits the Inflammatory Response and Improves Survival in CLP-Induced SepticMice. Int J Mol Sci. 2017 Dec 18;18 (12) . pii: E2744.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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