GGFG-PAB-MMAE
GGFG-PAB-MMAE (Comp 58054-1) is a drug-linker conjugate for ADC. GGFG-PAB-MMAE contains the ADC linker (GGFG-PAB) and a potent tubulin polymerization inhibitor MMAE.
Product Specifications
CAS Number
3049886-19-0
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC; Microtubule/Tubulin
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ggfg-pab-mmae.html
Purity
99.27
Solubility
DMSO : 120 mg/mL (ultrasonic)
Smiles
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC(CNC([C@@H](NC(CNC(CN)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)OC)=O
Molecular Formula
C62H92N10O13
Molecular Weight
1185.45
References & Citations
[1]Jinkun Huang, et al. Highly stable targeted linker-drug conjugate. US20240293570A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Auristatin
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC680525-500 1x 500 µL
CD63 (MX-49.129.5), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040034-500 1x 500 µL
Cytokeratin 8/18 (C-51), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880270-500 1x 500 µL
Fibronectin (HFN7.1), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880391-100 1x 100 µL
CD81 / TAPA-1 (1.3.3.22), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC941022-500 1x 500 µL
Hepatocyte Specific (CPS1/1022), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details