1alpha-Hydroxy VD4
1alpha-Hydroxy VD4, a 1alpha (OH) D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells.
Product Specifications
CAS Number
[143032-85-3]
Product Name Alternative
1α-Hydroxy vitamin D4
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
VD/VDR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/1alpha-hydroxy-vd4.html
Purity
98.41
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C=C1[C@@H](O)C[C@H](O)C/C1=C/C=C2[C@@](CC[C@@H]3[C@H](C)CC[C@H](C)C(C)C)([H])[C@]3(C)CCC/2
Molecular Formula
C28H46O2
Molecular Weight
414.66
Precautions
H302, H315, H319, H335
References & Citations
[1]M Makishima, et al. Growth inhibition and differentiation induction in human monoblastic leukaemia cells by 1alpha-hydroxyvitamin D derivatives and their enhancement by combination with hydroxyurea. British Journal of Cancer (1998) 77, 33-39
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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