NSC 698600
NSC 698600 is a potent PCAF inhibitor, with IC50 of 6.51 μM (PCAF/H31-21) . NSC 698600 exhibits good activity of inhibiting the proliferation of cancer cells[1].
Product Specifications
CAS Number
908069-17-0
UNSPSC
12352005
Target
Histone Acetyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nsc-698600.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=CC(C)=CN=C2SN1C3=CC=C(C=C3)OC
Molecular Formula
C14H12N2O2S
Molecular Weight
272.32
References & Citations
[1]Furdas SD, et al. Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors. Bioorg Med Chem. 2011 Jun 15;19 (12) :3678-89.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GCN5/PCAF
Available Sizes
Frequently Asked Questions
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