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NSC 698600

NSC 698600 is a potent PCAF inhibitor, with IC50 of 6.51 μM (PCAF/H31-21) . NSC 698600 exhibits good activity of inhibiting the proliferation of cancer cells[1].

Product Specifications

CAS Number

908069-17-0

UNSPSC

12352005

Target

Histone Acetyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nsc-698600.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=CC(C)=CN=C2SN1C3=CC=C(C=C3)OC

Molecular Formula

C14H12N2O2S

Molecular Weight

272.32

References & Citations

[1]Furdas SD, et al. Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors. Bioorg Med Chem. 2011 Jun 15;19 (12) :3678-89.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

GCN5/PCAF

Available Sizes

Frequently Asked Questions

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