Oxotremorine (sesquifumarate)
Oxotremorine sesquifumarate is a mAChR agonist that mainly activates M2 receptors. Oxotremorine sesquifumarate can be used for neurological research[1][2].
Product Specifications
CAS Number
17360-35-9
UNSPSC
12352005
Hazard Statement
H300+H310+H330
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/oxotremorine-sesquifumarate.html
Purity
98.0
Solubility
DMSO : 125 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C1N(CC#CCN2CCCC2)CCC1.O=C(O)/C=C/C(O)=O
Molecular Formula
C12H18N2O.3/2C4H4O4
Molecular Weight
380.38
Precautions
H300+H310+H330
References & Citations
[1]M Das, D K Ganguly, et al. Enhancement by oxotremorine of acetylcholine release from the rat phrenic nerve. Br J Pharmacol. 1978 Feb;62 (2) :195-8.|[2]Zhiyang Song, et al. Muscarinic receptor activation potentiates the effect of spinal cord stimulation on pain-related behavior in rats with mononeuropathy. Neurosci Lett. 2008 May 2;436 (1) :7-12.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAChR2
Available Sizes
Frequently Asked Questions
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