Oxotremorine (sesquifumarate)

Oxotremorine sesquifumarate is a mAChR agonist that mainly activates M2 receptors. Oxotremorine sesquifumarate can be used for neurological research[1][2].

Product Specifications

CAS Number

[17360-35-9]

UNSPSC

12352005

Hazard Statement

H300+H310+H330

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/oxotremorine-sesquifumarate.html

Purity

98.0

Solubility

DMSO : 125 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

O=C1N(CC#CCN2CCCC2)CCC1.O=C(O)/C=C/C(O)=O

Molecular Formula

C12H18N2O.3/2C4H4O4

Molecular Weight

380.38

Precautions

H300+H310+H330

References & Citations

[1]M Das, D K Ganguly, et al. Enhancement by oxotremorine of acetylcholine release from the rat phrenic nerve. Br J Pharmacol. 1978 Feb;62 (2) :195-8.|[2]Zhiyang Song, et al. Muscarinic receptor activation potentiates the effect of spinal cord stimulation on pain-related behavior in rats with mononeuropathy. Neurosci Lett. 2008 May 2;436 (1) :7-12.