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PLpro-IN-2

PLpro-IN-2 (Compound 16) is an inhibitor for SARS-CoV-2 papain-like protease (PLpro), with an IC50 of 0.25 μM[1].

Product Specifications

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/plpro-in-2.html

Solubility

10 mM in DMSO

Smiles

O=C(OCC)CCCNCC1=CC=C(C2=CC=CC([C@H](NC(C3=CC(NC4CNC4)=CC=C3C)=O)C)=C2)S1

Molecular Formula

C30H38N4O3S

Molecular Weight

534.71

References & Citations

[1]Wang X, et al., Chemical Space Profiling of SARS-CoV-2 PLpro Using DNA-Encoded Focused Libraries[J]. ACS Medicinal Chemistry Letters, 2024.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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