Allylestrenol
Allylestrenol is an orally active synthetic anti-androgen sexualsteroid. Allylestrenol can prevent miscarriage in vivo. Allylestrenol significantly affects testosterone progesterone level in rat model. Allylestrenol can reduce ventral prostate weight in rat model[1][2].
Product Specifications
CAS Number
432-60-0
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
Androgen Receptor; Progesterone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neuromodulation
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/Allylestrenol.html
Concentration
10mM
Purity
98.91
Solubility
DMSO : ≥ 50 mg/mL
Smiles
C[C@@]12[C@](O)(CC=C)CC[C@@]1([H])[C@]3([H])CCC4=CCCC[C@]4([H])[C@@]3([H])CC2
Molecular Formula
C21H32O
Molecular Weight
300.48
Precautions
H315, H319, H335
References & Citations
[1]Pap E, et al. Effect of prenatal allylestrenol treatment (hormonal imprinting) on the serum testosterone and progesterone level in adult rats. Gen Pharmacol. 1995 Mar;26 (2) :365-7.|[2]Yasuda, N., et al., (1997) . Effects of steroid 5alpha-reductase inhibitor ONO-9302 and anti-androgen allylestrenol on the prostatic growth, and plasma and prostatic hormone levels in rats. Japanese journal of pharmacology, 74 (3), 243–252.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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