Procaterol (hydrochloride hemihydrate)

Procaterol hydrochloride hemihydrate is an orally active β2 adrenoreceptor agonist. Procaterol hydrochloride hemihydrate can be used for the research of asthma[1][2][3].

Product Specifications

CAS Number

[81262-93-3]

Product Name Alternative

OPC 2009 (hydrochloride hemihydrate)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-anti-virus

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/procaterol-hydrochloride-hemihydrate.html

Purity

99.88

Solubility

H2O : 25 mg/mL (ultrasonic)

Smiles

O[C@H]([C@H](NC(C)C)CC)C1=C(C=CC(N2)=O)C2=C(O)C=C1.Cl.[0.5H2O]

Molecular Formula

C16H23ClN2O3.1/2H2O

Molecular Weight

335.82

Precautions

H302, H315, H319, H335

References & Citations

[1]Tukiainen H, et al. Comparison between oral procaterol and salbutamol in patients with bronchial asthma. Curr Med Res Opin. 1988;11 (4) :236-41. |[2]Mirza ZN, et al. Inhaled procaterol inhibits histamine-induced airflow obstruction and microvascular leakage in guinea-pig airways with allergic inflammation. Clin Exp Allergy. 1998 May;28 (5) :644-52. |[3]Ohkura N, et al. Bronchoconstriction-triggered cough in conscious guinea pigs. Exp Lung Res. 2009 May;35 (4) :296-306. |[4]Yamaya M, et al. Procaterol inhibits rhinovirus infection in primary cultures of human tracheal epithelial cells. Eur J Pharmacol. 2011 Jan 10;650 (1) :431-44. |[5]Koyama S, et al. Procaterol inhibits IL-1beta- and TNF-alpha-mediated epithelial cell eosinophil chemotactic activity. Eur Respir J. 1999 Oct;14 (4) :767-75. |[6]Deng Z, et al. Procaterol but not dexamethasone protects 16HBE cells from H₂O₂-induced oxidative stress. J Pharmacol Sci. 2014;125 (1) :39-50.