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6-Methylpurine riboside

6-Methylpurine riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

[14675-48-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others; Cancer

Assay Protocol

https://www.medchemexpress.com/6-methylpurine-riboside.html

Purity

96.92

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=NC3=C(N=CN=C32)C

Molecular Formula

C11H14N4O4

Molecular Weight

266.26

Precautions

H302, H315, H319, H335

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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