LB-102
LB-102 is an orally active inhibitor of dopamine D2, D3, and 5-HT7 receptors, which can be used in research on schizophrenia and other psychiatric disorders[1].
Product Specifications
CAS Number
2227154-23-4
UNSPSC
12352211
Target
5-HT Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lb-102.html
Smiles
CCN1CCCC1CNC(C2=CC(S(=O)(CC)=O)=C(C=C2OC)NC)=O
Molecular Formula
C18H29N3O4S
Molecular Weight
383.51
References & Citations
[1]Wong D F, et al. PET clinical study of novel antipsychotic LB-102 demonstrates unexpectedly prolonged dopamine receptor target engagement[J]. Neuropsychopharmacology, 2024: 1-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
5-HT7 Receptor
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