I5B2
Product Specifications
UNSPSC Description
I5B2 is an angiotensin I converting enzyme inhibitor (IC50=0.091 μM) that can be isolated from the culture medium of Actinomycete actininadura sp. No. 937ZE-1. I5B2 can be used in the study of hypertension[1].
Target Antigen
Angiotensin-converting Enzyme (ACE)
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/i5b2.html
Smiles
OC(C=C1)=CC=C1C[C@H](NC([C@@H](NC)C(C)C)=O)C(NC(P(O)(O)=O)CC2=CC=C(C=C2)O)=O
Molecular Weight
493.49
References & Citations
[1]KIDO, et al. "Isolation and characterization of I5B2, a new phosphorus containing inhibitor of angiotensin I converting enzyme produced by Actinomadura sp." The Journal of antibiotics 37.9 (1984): 965-969.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-119195/I5B2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-119195/
Clinical Information
No Development Reported
CAS Number
93768-49-1
Curated Selection
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