I5B2

I5B2 is an angiotensin I converting enzyme inhibitor (IC50=0.091 μM) that can be isolated from the culture medium of Actinomycete actininadura sp. No. 937ZE-1. I5B2 can be used in the study of hypertension[1].

Product Specifications

CAS Number

[93768-49-1]

UNSPSC

12352005

Target

Angiotensin-converting Enzyme (ACE)

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/i5b2.html

Smiles

OC(C=C1)=CC=C1C[C@H](NC([C@@H](NC)C(C)C)=O)C(NC(P(O)(O)=O)CC2=CC=C(C=C2)O)=O

Molecular Formula

C23H32N3O7P

Molecular Weight

493.49

References & Citations

[1]KIDO, et al. "Isolation and characterization of I5B2, a new phosphorus containing inhibitor of angiotensin I converting enzyme produced by Actinomadura sp." The Journal of antibiotics 37.9 (1984) : 965-969.