Human NPR1 / NPRA Protein, Fc Tag (MALS verified)
Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
Product Specifications
Background
Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 75.3 kDa. The protein migrates as 90-120 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P16066-1
Expression Region
Gly 33 - Glu 473
Host
HEK293
Target
NPR1
Conjugation
Unconjugated
Tag
C-Fc
Source
Human
Stability
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Bioactivity
Immobilized Human NPR1, Fc Tag (Cat. No. NP1-H5259) at 5 μg/mL (100 μL/well) can bind Anti-NPR1 antibody with a linear range of 0.6-20 ng/mL (Routinely tested).
Format
Powder
Buffer
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
75.3 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
500ug*2
Host or Source
HEK293
Species
Human
Protein ID
P16066-1
Preservative
Trehalose
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