P38α inhibitor 1
P38α inhibitor 1 is a p38α inhibitor extracted from patent WO 2008076265 A1.
Product Specifications
CAS Number
[1034189-82-6]
UNSPSC
12352005
Target
Autophagy; p38 MAPK
Type
Reference compound
Related Pathways
Autophagy; MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/p38_alpha__inhibitor_1.html
Purity
98.91
Solubility
DMSO : ≥ 125 mg/mL
Smiles
O=C(C1=CC2=C(C=C1OC3=CC=C(F)C=C3F)C=NN2CC(C)C)NCCN(C)C
Molecular Formula
C22H26F2N4O2
Molecular Weight
416.46
References & Citations
[1]Baker W, et al. Monophosphates as mutual prodrugs of anti-inflammatory signal transduction modulators (aistm's) and β-agonists for the treatment of pulmonary inflammation and bronchoconstriction. WO 2008076265 A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P38α
Available Sizes
Curated Selection
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