BDS-II

BDS-II is a peptide toxin, and is composed of 43 amino acids. BDS-II is a selective Kv3.4 channel inhibitor[1].

Product Specifications

UNSPSC

12352209

Target

Sodium Channel

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bds-ii.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](C)C(N1[C@@H](CCC1)C(N[C@@H](CSSC[C@@H]2NC3=O)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CCCCN)C(N[C@@H](CC6=CNC7=CC=CC=C67)C(N8[C@@H](CCC8)C(N[C@@H](CC(N)=O)C(N[C@H]3[C@@H](C)CC)=O)=O)=O)=O)=O)=O)NC9=O)C(N%10[C@@H](CCC%10)C(NCC(N[C@@H](CCCCN)C(N%11[C@@H](CCC%11)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC%12=CNC%13=CC=CC=C%12%13)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC%14=CC=C(C=C%14)O)C(N%15[C@@H](CCC%15)C(N[C@@H](CC%16=CNC=N%16)C(O)=O)=O)=O)=O)NC2=O)C(N%17[C@@H](CCC%17)C(NCC(NCC(N[C@@H](CC%18=CC=C(C=C%18)O)C(NCC(N[C@@H](CC%19=CC=C(C=C%19)O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(N[C@H]9CC(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N

Molecular Formula

C214H301N57O57S6

Molecular Weight

4776.42

References & Citations

[1]S Diochot, et al. Sea anemone peptides with a specific blocking activity against the fast inactivating potassium channel Kv3.4. J Biol Chem. 1998 Mar 20;273 (12) :6744-9.