Ac-hMCH (6-16) -NH2
Ac-hMCH (6-16) -NH2 binds to and activates equally well both human MCH receptors present in the brain (non-selective agonist), with IC50 values of 0.16 nM and 2.7 nM for MCH-1R and MCH-2R[1].
Product Specifications
CAS Number
353486-32-5
UNSPSC
12352209
Target
MCHR1 (GPR24)
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ac-hmch-6-16-nh2.html
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC1=O)=O)CCCNC(N)=N)=O)C(C)C)=O)CC(C=C2)=CC=C2O)=O)CCCNC(N)=N)N3[C@@](C(N[C@@H](CSSC[C@@H](C(N[C@H](C(N[C@H]1CC(C)C)=O)CCSC)=O)NC([C@@H](NC(C)=O)CCCNC(N)=N)=O)C(N)=O)=O)([H])CCC3
Molecular Formula
C58H97N21O13S3
Molecular Weight
1392.72
References & Citations
[1]Maria A Bednarek, et al. Synthesis and biological evaluation in vitro of a selective, high potency peptide agonist of human melanin-concentrating hormone action at human melanin-concentrating hormone receptor 1. J Biol Chem. 2002 Apr 19;277 (16) :13821-6.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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