5-Hydroxyindole-2-carboxylic Acid (Highly Pure)

<strong>5-Hydroxyindole-2-carboxylic Acid (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2016293_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 g_x000D_ <strong>Molecular Weight or Concentration:</strong> 177.16 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> 5-Hydroxyindole-2-carboxylic acid_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Pierson PD, Fettes A, Freichel C, Gatti-McArthur S, Hertel C, Huwyler J, Mohr P, Nakagawa T, Nettekoven M, Plancher JM, Raab S, Richter H, Roche O, Rodríguez Sarmiento RM, Schmitt M, Schuler F, Takahashi T, Taylor S, Ullmer C, Wiegand R. 5-hydroxyindole-2-carboxylic acid amides: novel histamine-3 receptor inverse agonists for the treatment of obesity J Med Chem. 2009 Jul 9;52(13):3855-68._x000D_ 2: Aroca P, Solano F, Garcia-Borrón JC, Lozano JA. Specificity of dopachrome tautomerase and inhibition by carboxylated indoles. Considerations on the enzyme active site Biochem J. 1991 Jul 15;277 ( Pt 2)(Pt 2):393-7._x000D_ 3: Cuevas AA, García-Castiñeiras S. Melanins and lens pigments: a comparative study P R Health Sci J. 1993 Jun;12(2):129-35._x000D_ 4: Ritschdorff ET, Plenert ML, Shear JB. Microsecond analysis of transient molecules using bi-directional capillary electrophoresis Anal Chem. 2009 Nov 1;81(21):8790-6._x000D_ 5: Du F, Zhou Q, Sun W, Yang C, Wu C, Wang L, Chen G. 5-Hydroxyindole-Based EZH2 Inhibitors Assembled via TCCA-Catalyzed Condensation and Nenitzescu Reactions Molecules. 2020 Apr 28;25(9):2059._x000D_ 6: Waclawiková B, Bullock A, Schwalbe M, Aranzamendi C, Nelemans SA, van Dijk G, El Aidy S. Gut bacteria-derived 5-hydroxyindole is a potent stimulant of intestinal motility via its action on L-type calcium channels PLoS Biol. 2021 Jan 22;19(1):e3001070._x000D_ 7: Southgate J, Sandler M. 5-hydroxyindole metabolism in pregnancy Adv Pharmacol (1962). 1968;6(Pt B):179-86._x000D_ 8: Moroni F, Carpenedo R, Mannaioni G, Galli A, Chiarugi A, Carlà V, Moneti G. Studies on the pharmacological properties of oxindole (2-hydroxyindole) and 5-hydroxyindole: are they involved in hepatic encephalopathy? Adv Exp Med Biol. 1997;420:57-73._x000D_ 9: Fredj Z, Ali M, Singh B, Dempsey E. Simultaneous voltammetric detection of 5-hydroxyindole-3-acetic acid and 5-hydroxytryptamine using a glassy carbon electrode modified with conducting polymer and platinised carbon nanofibers Mikrochim Acta. 2018 Aug 13;185(9):412._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/5036094">10: Murray-Lyon IM, Sandler M, Cheetham HD, Watts JA, Williams R. 5-Hydroxyindole-secreting rectal carcinoid tumour Gut. 1972 May;13(5):385-6. </a>_x000D_ _x000D_ <strong>Products Related to 5-Hydroxyindole-2-carboxylic Acid (Highly Pure) can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>