BChE-IN-17
BChE-IN-17 (compound 6n) is a potent and selective BChE inhibitor with IC50s of 10.5 nM and 32.5 nM for eqBChE and hBChE, respectively. BChE-IN-17 shows over 1000-fold selectivity to BChE against AChE. BChE-IN-17 shows low neurotoxicity and moderate neuroprotective effects[1].
Product Specifications
CAS Number
[2425632-57-9]
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bche-in-17.html
Purity
99.07
Solubility
DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
BrC1=CC(CN2CC(SC(NS(C3=CC=C(C)C=C3)(=O)=O)=C4C(OC)=O)=C4CC2)=CC=C1
Molecular Formula
C23H23BrN2O4S2
Molecular Weight
535.47
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE
Available Sizes
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