5′-Deoxy-5′-iodoguanosine
Product Specifications
UNSPSC Description
5'-Deoxy-5'-iodoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-deoxy-5-iodoguanosine.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(NC(N)=N1)N([C@@H]3O[C@@H]([C@H]([C@H]3O)O)CI)C=N2
Molecular Weight
393.14
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W039275/5-Deoxy-5-iodoguanosine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W039275/
Clinical Information
No Development Reported
CAS Number
68200-68-0
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