IDF-11774
IDF-11774 is a novel hypoxia-inducible factor α (HIFα) -1 inhibitor with an IC50 of 3.65 μM.
Product Specifications
CAS Number
[1429054-28-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HIF/HIF Prolyl-Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/IDF-11774.html
Purity
99.30
Solubility
DMSO : 60 mg/mL (ultrasonic; warming)
Smiles
CN1CCN(C(COC2=CC=C(C3(C4)CC5CC4CC(C5)C3)C=C2)=O)CC1
Molecular Formula
C23H32N2O2
Molecular Weight
368.51
Precautions
H302, H315, H319, H335
References & Citations
[1]Ban HS, et al. The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth. Cell Death Dis. 2017 Jun 1;8 (6) :e2843.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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