IDF-11774

IDF-11774 is a novel hypoxia-inducible factor α (HIFα) -1 inhibitor with an IC50 of 3.65 μM.

Product Specifications

CAS Number

[1429054-28-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

HIF/HIF Prolyl-Hydroxylase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/IDF-11774.html

Purity

99.30

Solubility

DMSO : 60 mg/mL (ultrasonic; warming)

Smiles

CN1CCN(C(COC2=CC=C(C3(C4)CC5CC4CC(C5)C3)C=C2)=O)CC1

Molecular Formula

C23H32N2O2

Molecular Weight

368.51

Precautions

H302, H315, H319, H335

References & Citations

[1]Ban HS, et al. The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth. Cell Death Dis. 2017 Jun 1;8 (6) :e2843.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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