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8-Bromo-5’-O- (4-cyanobenzyl) -2’,3’-di-O-isopropylidene adenosine

Selected Variant

HY-W000284

Size: 1 Each

8-Bromo-5’-O- (4-cyanobenzyl) -2’,3’-di-O-isopropylidene adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine , Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).

Product Specifications

CAS Number

1134156-53-8

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/8-bromo-5-o-4-cyanobenzyl-2-3-di-o-isopropylidene-adenosine.html

Solubility

10 mM in DMSO

Smiles

CC1(C)O[C@H]2[C@@H](O1)[C@H](N3C(N=CN=C4N)=C4N=C3Br)O[C@@H]2COCC5=CC=C(C#N)C=C5

Molecular Formula

C21H21BrN6O4

Molecular Weight

501.33

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26 (6) :1490-1500.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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