IL-17A inhibitor 4
IL-17A inhibitor 4 (Example 449) is a potent IL-17A inhibitor. IL-17A inhibitor 4 inhibits HTRF and NHK cells viability with IC50s of 0.028 and 0.0047 μM, respectively[1].
Product Specifications
UNSPSC
12352005
Target
Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/il-17a-inhibitor-4.html
Smiles
FC(F)(C1)[C@H]1CC(N[C@@H](C2=CC3=NC([C@H](C4CCC(F)(CC4)F)NC(C5=NON=C5C6CC6)=O)=CN3N=C2)C7(CCC7)C#N)=O
Molecular Formula
C30H32F4N8O3
Molecular Weight
628.62
References & Citations
[1]Douglas BEHENNA, et al. Imidazopyridazines as modulators of il-17. US, WO2021222404. 2021-11-04.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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